ELANE Antikörper

Produktnummer ABIN7880674

Der Kaninchen Monoklonal anti-ELANE Antikörper (Klon AOCI-5) (ABIN7880674) detektiert spezifisch ELANE in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ELANE Antikörper (ABIN7880674)

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ELANE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AOCI-5

Produktdetails anti-ELANE Antikörper

Verwendungszweck: Neutrophil Elastase Antibody

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Neutrophil Elastase / ELANE was used as the immunogen for the Neutrophil Elastase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Neutrophil Elastase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the Neutrophil Elastase antibody at -20oC.

Details zu ELANE

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Andere Bezeichnung: Neutrophil Elastase

Hintergrund: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. [RefSeq]

UniProt: P08246