DPYSL2 Antikörper

Produktnummer ABIN7880629

Der Kaninchen Polyklonal anti-DPYSL2 Antikörper (ABIN7880629) detektiert spezifisch DPYSL2 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DPYSL2 Antikörper (ABIN7880629)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYSL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-DPYSL2 Antikörper

Verwendungszweck: CRMP2 Antibody / DPYSL2

Aufreinigung: Antigen affinity purified

Immunogen: Amio acids KDRFQLTDCQIYEVLSV were used as the immunogen for the CRMP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CRMP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CRMP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Andere Bezeichnung: CRMP2

Hintergrund: Dihydropyrimidinase-related protein 2, also called Collapsin response mediator protein 2 (CRMP2), is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q16555

Pathways: Regulation of Cell Size