DPYSL2 Antikörper (AA 400-500)
Kurzübersicht für DPYSL2 Antikörper (AA 400-500) (ABIN7266769)
Target
Alle DPYSL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 400-500
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Verwendungszweck
- [KO Validated] CRMP2/DPYSL2 Rabbit pAb
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Sequenz
- RIAVGSDADL VIWDPDSVKT ISAKTHNSSL EYNIFEGMEC RGSPLVVISQ GKIVLEDGTL HVTEGSGRYI PRKPFPDFVY KRIKARSRLA ELRGVPRGLY D
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CRMP2/CRMP2/DPYSL2 (NP_001377.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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Andere Bezeichnung
- DPYSL2
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Hintergrund
- This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,DPYSL2,CRMP-2,CRMP2,DHPRP2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2,Cell Biology & Developmental Biology,Microtubules,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DPYSL2
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Molekulargewicht
- 58kDa/62kDa
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Gen-ID
- 1808
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UniProt
- Q16555
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Pathways
- Regulation of Cell Size
Target
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