DKK2 Antikörper

Produktnummer ABIN7880625

Der Maus Monoklonal anti-DKK2 Antikörper wird verwendet zum Nachweis von DKK2 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für DKK2 Antikörper (ABIN7880625)

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DKK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1833CT856-7-20

Produktdetails anti-DKK2 Antikörper

Verwendungszweck: DKK2 Antibody

Aufreinigung: Protein G purified

Immunogen: Recombinant human DKK2 was used as the immunogen for the DKK2 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the DKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DKK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu DKK2

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Andere Bezeichnung: DKK2

Hintergrund: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). [UniProt]

UniProt: Q9UBU2

Pathways: WNT Signalweg