Rekombinanter Desmoglein 1 Antikörper
Kurzübersicht für Rekombinanter Desmoglein 1 Antikörper (ABIN7880622)
Target
Alle Desmoglein 1 (DSG1) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Desmoglein 1 Antibody / DSG1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant human DSG1 protein was used as the immunogen for the Desmoglein 1 antibody.
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Isotyp
- IgG, kappa
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anti-Desmoglein 1 (DSG1) antibody
DSG1 Reaktivität: Human IHC Wirt: Maus Monoclonal 32-2B unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 Reaktivität: Human IHC Wirt: Maus Monoclonal 544M unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (N-Term) antibodyDSG1 Reaktivität: Human, Maus, Ratte WB, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 384-539) antibodyDSG1 Reaktivität: Human IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 800-1049) antibodyDSG1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 710-961) antibodyDSG1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (Internal Region) antibodyVerified DSG1 Reaktivität: Human IHC, ELISA Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the Desmoglein 1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Desmoglein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Desmoglein 1 (DSG1)
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Andere Bezeichnung
- Desmoglein 1
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Hintergrund
- Recognizes a protein of ~150 kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms.Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
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UniProt
- Q02413
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Pathways
- Cell-Cell Junction Organization
Target
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