Der Kaninchen Polyklonal anti-CRB1 Antikörper (ABIN7880515) detektiert spezifisch CRB1 in WB, IHC (p) und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
CRB1
Reaktivität: Human
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 647
Applikationshinweise
Optimal dilution of the CRB1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
Store the CRB1 antibody at -20oC.
Target
CRB1
(Crumbs Homolog 1 (CRB1))
Andere Bezeichnung
CRB1
Hintergrund
Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.