Rekombinanter CHMP2B Antikörper

Produktnummer ABIN7880390

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CHMP2B in WB, IHC (p) und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CHMP2B Antikörper (ABIN7880390)

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CHMP2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Klon: 25C36

Produktdetails anti-CHMP2B Antikörper

Verwendungszweck: CHMP2B Antibody / Charged multivesicular body protein 2b

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to Charged multivesicular body protein 2b protein was used as the immunogen for the CHMP2B antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CHMP2B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CHMP2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CHMP2B

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Andere Bezeichnung: CHMP2B

Hintergrund: Charged multivesicular body protein 2b (CHMP2B) is a component of the endosomal sorting complex required for transport III (ESCRT-III). It plays a critical role in multivesicular body formation, membrane fission, and the sorting of ubiquitinated proteins for lysosomal degradation. CHMP2B is essential for maintaining proper endosomal trafficking and cellular protein homeostasis.

Mutations in CHMP2B have been linked to neurodegenerative disorders, including frontotemporal dementia and amyotrophic lateral sclerosis. Research on CHMP2B helps elucidate mechanisms of vesicular transport, neuronal maintenance, and protein quality control, making it relevant in both basic and disease-focused studies.

Using a high-quality CHMP2B antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CHMP2B antibody from NSJ Bioreagents provides reliable and reproducible performance for studies in membrane trafficking, neurodegeneration, and cellular signaling. Selecting the right CHMP2B antibody is essential for obtaining consistent and meaningful results.

UniProt: Q9UQN3