CHMP2B Antikörper (AA 1-213)

Produktnummer ABIN7147523

Produktdetails anti-CHMP2B Antikörper

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Bindungsspezifität: AA 1-213

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP2B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Charged multivesicular body protein 2b protein (1-213AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHMP2B

Target: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Andere Bezeichnung: CHMP2B (CHMP2B Produkte)

Synonyme: ALS17 antikoerper, CHMP2.5 antikoerper, DMT1 antikoerper, VPS2-2 antikoerper, VPS2B antikoerper, 1190006E07Rik antikoerper, RGD1306781 antikoerper, chmp2b antikoerper, chmp2bl antikoerper, zgc:77025 antikoerper, si:ch211-224m9.5 antikoerper, CHMP2B antikoerper, cg4618 antikoerper, chmp2.5 antikoerper, dmt1 antikoerper, vps2-2 antikoerper, vps2b antikoerper, CHMP2b-B antikoerper, chmp2b-a antikoerper, chmp2b-b antikoerper, charged multivesicular body protein 2B antikoerper, charged multivesicular body protein 2Bb antikoerper, charged multivesicular body protein 2Ba antikoerper, charged multivesicular body protein 2B pseudogene antikoerper, charged multivesicular body protein 2B S homeolog antikoerper, charged multivesicular body protein 2B L homeolog antikoerper, CHMP2B antikoerper, Chmp2b antikoerper, chmp2bb antikoerper, chmp2ba antikoerper, LOC747711 antikoerper, chmp2b.S antikoerper, chmp2b.L antikoerper

Hintergrund:

Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.

Aliases: ALS17 antibody, Charged multivesicular body protein 2b antibody, CHM2B_HUMAN antibody, CHMP family, member 2B antibody, CHMP2.5 antibody, CHMP2b antibody, Chromatin modifying protein 2b antibody, Chromatin-modifying protein 2b antibody, DMT1 antibody, hVps2-2 antibody, Vacuolar protein sorting 2, yeast, homolog of, B antibody, Vacuolar protein sorting 2-2 antibody, Vacuolar protein sorting-associated protein 2-2 antibody, VPS2 homolog B antibody, Vps2-2 antibody, VPS2B antibody

UniProt: Q9UQN3