Rekombinanter CDX2 Antikörper

Produktnummer ABIN7880212

Der Maus Monoklonal anti-CDX2 Antikörper (Klon rCDX2-6921) (ABIN7880212) detektiert spezifisch CDX2 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CDX2 Antikörper (ABIN7880212)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDX2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RCDX2-6921

Produktdetails anti-CDX2 Antikörper

Verwendungszweck: Recombinant Caudal Type Homeobox 2 Antibody / CDX2

Aufreinigung: Protein A/G affinity

Immunogen: A synthetic peptide from human CDX2 protein was used as the immunogen for the recombinant Caudal Type Homeobox 2 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Caudal Type Homeobox 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Caudal Type Homeobox 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Andere Bezeichnung: Caudal Type Homeobox 2

Hintergrund: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance