Cathepsin D Antikörper
Kurzübersicht für Cathepsin D Antikörper (ABIN7880203)
Target
Alle Cathepsin D (CTSD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- CTSD Antibody / Cathepsin D
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Purified His-tagged CTSD protein was used as the immunogen for the CTSD antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the CTSD antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CTSD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cathepsin D (CTSD)
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Andere Bezeichnung
- CTSD
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Hintergrund
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease.
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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