Cathepsin B Antikörper

Produktnummer ABIN7880201

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Cathepsin B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Cathepsin B Antikörper (ABIN7880201)

Target: Cathepsin B (CTSB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AAFO-3

Produktdetails anti-Cathepsin B Antikörper

Verwendungszweck: CTSB Antibody / Cathepsin B

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Cathepsin B / CTSB was used as the immunogen for the CTSB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CTSB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CTSB antibody at -20oC.

Details zu Cathepsin B

Target: Cathepsin B (CTSB)

Andere Bezeichnung: CTSB

Hintergrund: The CTSB gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. [RefSeq]

UniProt: P07858

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades