CTNND1 Antikörper

Produktnummer ABIN7880196

Der Kaninchen Monoklonal anti-CTNND1 Antikörper wird verwendet zum Nachweis von CTNND1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CTNND1 Antikörper (ABIN7880196)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CTNND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: GI-3

Produktdetails anti-CTNND1 Antikörper

Verwendungszweck: p120 Catenin Antibody / CTNND1

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Catenin delta 1 / p120 Catenin / CTNND1 was used as the immunogen for the p120 Catenin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the p120 Catenin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the p120 Catenin antibody at -20oC.

Details zu CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Andere Bezeichnung: p120 Catenin

Hintergrund: P120 Catenin binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. [UniProt]

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling