Der Maus Monoklonal anti-BCL6 Antikörper (Klon PCRP-BCL6-1D3) (ABIN7880041) detektiert spezifisch BCL6 in FACS und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
BCL6
Reaktivität: Human
WB
Wirt: Maus
Monoclonal
BCL6-1475
unconjugated
Applikationshinweise
Optimal dilution of the Bcl6 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Bcl6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
BCL6
(B-Cell CLL/lymphoma 6 (BCL6))
Andere Bezeichnung
Bcl6
Hintergrund
Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.