ACP2 Antikörper

Produktnummer ABIN7879861

Der Kaninchen Polyklonal anti-ACP2 Antikörper (ABIN7879861) detektiert spezifisch ACP2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für ACP2 Antikörper (ABIN7879861)

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACP2 Antikörper

Verwendungszweck: ACP2 Antibody / Lysosomal Acid Phosphatase

Sequenz: RSLRFVTLLY RHGDRSPVKT YPKDPYQE

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids RSLRFVTLLYRHGDRSPVKTYPKDPYQE were used as the immunogen for the ACP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ACP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ACP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ACP2

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Andere Bezeichnung: ACP2

Hintergrund: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

UniProt: P11117