ACP2 Antikörper (Middle Region)

Produktnummer ABIN2782134

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ACP2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für ACP2 Antikörper (Middle Region) (ABIN2782134)

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ACP2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ACP2 Antibody - middle region

Sequenz: VPITEDRLLK FPLGPCPRYE QLQNETRQTP EYQNESSRNA QFLDMVANET

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ACP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45143-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ACP2

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Andere Bezeichnung: ACP2

Hintergrund:

Background Information: ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Lysosomal acid phosphatase is comprised of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Acid phosphatase 2, lysosomal

Alternative Symbols: LAP

Protein Name: Lysosomal acid phosphatase

Molekulargewicht: 45kDa

Gen-ID: 53

NCBI Accession: NP_001601

UniProt: P11117