ERN1 Antikörper (pSer724)
Kurzübersicht für ERN1 Antikörper (pSer724) (ABIN7879768)
Target
Alle ERN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- pSer724
-
Verwendungszweck
- Phospho-IRE1 Antibody (pS724)
-
Aufreinigung
- Affinity purified
-
Immunogen
- A synthetic peptide specific to human IRE1 / ERN1 (surrounding pS724) was used as the immunogen for the phospho-IRE1 antibody.
-
Isotyp
- IgG
-
-
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 Reaktivität: Human, Maus, Ratte, Schwein WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 Reaktivität: Human WB, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Monoclonal 1F12 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer724) antibodyERN1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB5220 unconjugated Recombinant Antibody
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- Optimal dilution of the phospho-IRE1 antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store the phospho-IRE1 antibody at -20oC.
-
-
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
-
Andere Bezeichnung
- IRE1
-
Hintergrund
- IRE1 is a serine/threonine-protein kinase and endoribonuclease that acts as a key sensor for the endoplasmic reticulum unfolded protein response (UPR). In unstressed cells, the ER luminal domain is maintained in its inactive monomeric state by binding to the ER chaperone HSPA5/BiP. Accumulation of misfolded protein in the ER causes release of HSPA5/BiP, allowing the luminal domain to homodimerize, promoting autophosphorylation of the kinase domain and subsequent activation of the endoribonuclease activity. [UniProt]
-
UniProt
- O75460
-
Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
Target
-
