NUMA1 Antikörper (pSer395) (Cy3)

Produktnummer ABIN744446

Produktdetails anti-NUMA1 Antikörper (Cy3)

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Bindungsspezifität: pSer395

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMA1 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NuMA around the phosphorylation site of Ser395

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NUMA1

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Andere Bezeichnung: NuMA (NUMA1 Produkte)

Synonyme: NUMA antikoerper, 6720401E04Rik antikoerper, AA764025 antikoerper, AL022610 antikoerper, AU014979 antikoerper, NUMA1 antikoerper, NuMA antikoerper, SP-H antikoerper, numa antikoerper, numa1 antikoerper, nuclear mitotic apparatus protein 1 antikoerper, nuclear mitotic apparatus protein 1 S homeolog antikoerper, NUMA1 antikoerper, Numa1 antikoerper, numa1 antikoerper, numa1.S antikoerper

Hintergrund:

Synonyms: NUMA 1, NuMA protein, NUMA1, SP H antigen, Structural nuclear protein, Centrophilin stabilizes mitotic spindle in mitotic cells, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein.

Background: NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis.

Gen-ID: 4926

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, M Phase