Rekombinanter Retinoblastoma Protein (Rb) Antikörper (full length)

Produktnummer ABIN7878913

Der Kaninchen Monoklonal anti-Retinoblastoma Protein (Rb) Antikörper (Klon RB1-7080R) (ABIN7878913) detektiert spezifisch Retinoblastoma Protein (Rb) in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Retinoblastoma Protein (Rb) Antikörper (full length) (ABIN7878913)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB1-7080R

Produktdetails anti-Retinoblastoma Protein (Rb) Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant Retinoblastoma Antibody

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant human full-length protein was used as the immunogen for the recombinant Retinoblastoma antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Retinoblastoma antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Retinoblastoma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Andere Bezeichnung: Retinoblastoma

Hintergrund: Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases