NME1 Antikörper (full length)
Kurzübersicht für NME1 Antikörper (full length) (ABIN7878716)
Target
Alle NME1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- NME1 Antibody / NM23 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant full-length human NME1 protein was used as the immunogen for this NME1 antibody.
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal dilution of the NME1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the NME1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Andere Bezeichnung
- NME1
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Hintergrund
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.
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UniProt
- P15531
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Pathways
- Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Target
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