JunB Antikörper (full length)

Produktnummer ABIN7878467

Dieser Maus Monoklonal Antikörper detektiert spezifisch JunB in IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für JunB Antikörper (full length) (ABIN7878467)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JunB Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-JUNB-3G11

Produktdetails anti-JunB Antikörper

Bindungsspezifität: full length

Verwendungszweck: JUNB Antibody

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human JUNB protein was used as the immunogen for the JUNB antibody.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the JUNB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the JUNB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Andere Bezeichnung: JUNB

Hintergrund: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

UniProt: P17275