JunB Antikörper (full length)

Produktnummer ABIN7878466

Der Maus Monoklonal anti-JunB Antikörper (Klon PCRP-JUNB-3G11) (ABIN7878466) detektiert spezifisch JunB in IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für JunB Antikörper (full length) (ABIN7878466)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JunB Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-JUNB-3G11

Produktdetails anti-JunB Antikörper

Bindungsspezifität: full length

Verwendungszweck: JUNB Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human JUNB protein was used as the immunogen for the JUNB antibody.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the JUNB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the JUNB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Andere Bezeichnung: JUNB

Hintergrund: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

UniProt: P17275