GLG1 Antikörper (full length)

Produktnummer ABIN7878314

Dieser Maus Monoklonal Antikörper detektiert spezifisch GLG1 in IHC (fp) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GLG1 Antikörper (full length) (ABIN7878314)

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLG1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Güteklasse: Carrier-free

Klon: GLG1-4830

Produktdetails anti-GLG1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: GLG1 Antibody / Golgi Glycoprotein 1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the GLG1 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GLG1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the GLG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu GLG1

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Andere Bezeichnung: GLG1

Hintergrund: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

UniProt: Q92896