Rekombinanter GLG1 Antikörper

Produktnummer ABIN7862906

Der Kaninchen Monoklonal anti-GLG1 Antikörper wird verwendet zum Nachweis von GLG1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter GLG1 Antikörper (ABIN7862906)

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GLG1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: GLG1-7174R

Produktdetails anti-GLG1 Antikörper

Verwendungszweck: Recombinant GLG1 (Golgi Glycoprotein 1) (Marker for Human Cells) Antibody

Spezifität: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GLG1 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GLG1

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Andere Bezeichnung: GLG1

Hintergrund:

CFR-1, Cysteine-rich fibroblast growth factor receptor, E-selectin ligand-1 (ESL-1), Golgi Glycoprotein 1 (GLG1), Golgi apparatus protein 1, Golgi sialoglycoprotein MG-160, Slectin, endothelial cell, ligand

A431 or HeLa cells. Human placenta, HePG2, tonsil or ovary.

Molekulargewicht: 134kDa

Gen-ID: 2734, 109731

UniProt: Q92896