Rekombinanter CGA Antikörper (full length)

Produktnummer ABIN7878307

Der Maus Monoklonal anti-CGA Antikörper (Klon rCHGA-9612) (ABIN7878307) detektiert spezifisch CGA in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CGA Antikörper (full length) (ABIN7878307)

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CGA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RCHGA-9612

Produktdetails anti-CGA Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant CgA Antibody / Chromogranin A

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human Chromogranin A protein was used as the immunogen for the recombinant CgA antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CgA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant CgA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CGA

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Andere Bezeichnung: CgA

Hintergrund: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

UniProt: P10645

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism