DMRT2 Antikörper (full length)

Produktnummer ABIN7878145

Der Maus Monoklonal anti-DMRT2 Antikörper (Klon PCRP-DMRT2-1B11) (ABIN7878145) detektiert spezifisch DMRT2 in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DMRT2 Antikörper (full length) (ABIN7878145)

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DMRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: PCRP-DMRT2-1B11

Produktdetails anti-DMRT2 Antikörper

Bindungsspezifität: full length

Verwendungszweck: DMRT2 Antibody

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human DMRT2 protein was used as the immunogen for the DMRT2 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DMRT2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the DMRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu DMRT2

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Andere Bezeichnung: DMRT2

Hintergrund: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

UniProt: Q9Y5R5