DMRT2 Antikörper

Produktnummer ABIN7504176

Produktdetails anti-DMRT2 Antikörper

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DMRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human DMRT2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Positive Control: HeLa or MCF-7 cells.

Known Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu DMRT2

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Andere Bezeichnung: DMRT2 (DMRT2 Produkte)

Synonyme: dmrt2 antikoerper, zDmrt2 antikoerper, Terra antikoerper, DMRT2 antikoerper, dmrt2a antikoerper, MGC131063 antikoerper, Terra-like antikoerper, Ci-DMRT2 antikoerper, doublesex and mab-3 related transcription factor 2 antikoerper, doublesex and mab-3 related transcription factor 2a antikoerper, doublesex and mab-3 related transcription factor 2 L homeolog antikoerper, doublesex and mab-3 related transcription factor 2b antikoerper, DMRT2 antikoerper, dmrt2a antikoerper, Dmrt2 antikoerper, dmrt2 antikoerper, dmrt2.L antikoerper, LOC778577 antikoerper, dmrt2b antikoerper

Hintergrund: Doublesex and mab-3 related transcription factor 2, doublesex-like 2 protein (DSXL-2), terra like protein antibody,DMRT2 (Transcription Factor)
Cellular localisation: Nucleus

Molekulargewicht: 62kDa

Gen-ID: 10655, 59506

UniProt: Q9Y5R5