CKM Antikörper (full length)

Produktnummer ABIN7878038

Dieser Maus Monoklonal Antikörper detektiert spezifisch CKM in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CKM Antikörper (full length) (ABIN7878038)

Target: CKM (Creatine Kinase, Muscle (CKM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CKMM-3341

Produktdetails anti-CKM Antikörper

Bindungsspezifität: full length

Verwendungszweck: Creatine Kinase M Antibody / CKM

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant full-length CKM protein was used as the immunogen for the Creatine Kinase M antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Creatine Kinase M antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Creatine Kinase M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Andere Bezeichnung: Creatine Kinase M

Hintergrund: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

UniProt: P06732