Rekombinanter CD45RA Antikörper (full length)

Produktnummer ABIN7877895

Der Maus Monoklonal anti-CD45RA Antikörper wird verwendet zum Nachweis von CD45RA in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter CD45RA Antikörper (full length) (ABIN7877895)

Target: CD45RA

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD45RA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: RPTPRC-7283

Produktdetails anti-CD45RA Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant CD45RA Antibody (Leukocyte marker) (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human PTPRC protein was used as the immunogen for the recombinant CD45RA antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CD45RA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant CD45RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CD45RA

Target: CD45RA

Andere Bezeichnung: CD45RA

Hintergrund: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

UniProt: P08575