CNOT10 Antikörper (full length)

Produktnummer ABIN7877840

Dieser Maus Monoklonal Antikörper detektiert spezifisch CNOT10 in WB, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CNOT10 Antikörper (full length) (ABIN7877840)

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNOT10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-CNOT10-1D5

Produktdetails anti-CNOT10 Antikörper

Bindungsspezifität: full length

Verwendungszweck: CNOT10 Antibody / CCR4-NOT transcription complex subunit 10 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the CNOT10 antibody.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CNOT10 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CNOT10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CNOT10

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Andere Bezeichnung: CNOT10

Hintergrund: CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.

UniProt: Q9H9A5