CEA Antikörper (full length) (CF®488A)

Produktnummer ABIN7877823

Der Maus Monoklonal anti-CEA Antikörper wird verwendet zum Nachweis von CEA in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für CEA Antikörper (full length) (CF®488A) (ABIN7877823)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEA Antikörper ist konjugiert mit CF®488A

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: C66-1009

Produktdetails anti-CEA Antikörper (CF®488A)

Bindungsspezifität: full length

Verwendungszweck: CEA Antibody / Carcinoembryonic Antigen

Aufreinigung: Protein G affinity chromatography

Immunogen: Human full-length recombinant CEA protein was used as the immunogen for this antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CEA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the CEA antibody at 2-8oC, protected from light.

Details zu CEA

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Andere Bezeichnung: CEA

Hintergrund: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

UniProt: P06731