Annexin A2 Antikörper (full length)

Produktnummer ABIN7877681

Dieser Maus Monoklonal Antikörper detektiert spezifisch Annexin A2 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Annexin A2 Antikörper (full length) (ABIN7877681)

Target: Annexin A2 (ANXA2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin A2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: 3D5-4

Produktdetails anti-Annexin A2 Antikörper

Bindungsspezifität: full length

Verwendungszweck: ANXA2 Antibody / Annexin A2 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the ANXA2 antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ANXA2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ANXA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Annexin A2

Target: Annexin A2 (ANXA2)

Andere Bezeichnung: ANXA2

Hintergrund: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

UniProt: P07355

Pathways: S100 Proteine