Rekombinanter YWHAE Antikörper (full length)
Kurzübersicht für Rekombinanter YWHAE Antikörper (full length) (ABIN7877576)
Target
Alle YWHAE Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- 14-3-3 epsilon Antibody / YWHAE (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant human full-length protein was used as the immunogen for the 14-3-3 epsilon antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the 14-3-3 epsilon antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the 14-3-3 epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- YWHAE (14-3-3 epsilon (YWHAE))
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Andere Bezeichnung
- 14-3-3 epsilon
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Hintergrund
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
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UniProt
- P62268
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Pathways
- Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase
Target
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