Rekombinanter UBA3 Antikörper (Catalytic Subunit)
Kurzübersicht für Rekombinanter UBA3 Antikörper (Catalytic Subunit) (ABIN7877514)
Target
Alle UBA3 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- Catalytic Subunit
-
Verwendungszweck
- UBA3 Antibody / Ubiquitin-activating enzyme 3 / UBE1C
-
Aufreinigung
- Affinity chromatography
-
Immunogen
- A synthetic peptide from human NEDD8-activating enzyme E1 catalytic subunit protein was used as the immunogen for the UBA3 antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the UBA3 antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store the UBA3 antibody at -20oC.
-
-
- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
-
Andere Bezeichnung
- UBA3
-
Hintergrund
- NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]
-
UniProt
- Q8TBC4
Target
-