UBA3 Antikörper (Catalytic Subunit)

Produktnummer ABIN7161136

Produktdetails anti-UBA3 Antikörper

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Bindungsspezifität: AA 234-463, Catalytic Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human NEDD8-activating enzyme E1 catalytic subunit protein (234-463AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UBA3

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Andere Bezeichnung: UBA3 (UBA3 Produkte)

Synonyme: UBE1C antikoerper, hUBA3 antikoerper, Ube1c antikoerper, ube1c antikoerper, wu:fb75e04 antikoerper, wu:fc37b11 antikoerper, zgc:55528 antikoerper, A830034N06Rik antikoerper, AI256736 antikoerper, AI848246 antikoerper, AW546539 antikoerper, ubiquitin like modifier activating enzyme 3 antikoerper, ubiquitin-like modifier activating enzyme 3 antikoerper, ubiquitin like modifier activating enzyme 3 S homeolog antikoerper, UBA3 antikoerper, Uba3 antikoerper, uba3 antikoerper, uba3.S antikoerper

Hintergrund:

Background: Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

Aliases: DKFZp566J164 antibody, EC 6.3.2. antibody, hUba3 antibody, MGC22384 antibody, NEDD8 activating enzyme E1 catalytic subunit antibody, NEDD8 activating enzyme E1C antibody, Nedd8 activating enzyme hUba3 antibody, NEDD8-activating enzyme E1 catalytic subunit antibody, NEDD8-activating enzyme E1C antibody, uba3 antibody, UBA3 ubiquitin activating enzyme E1 homolog antibody, UBA3_HUMAN antibody, UBE1C antibody, Ubiquitin activating enzyme 3 antibody, Ubiquitin activating enzyme E1C antibody, Ubiquitin-activating enzyme 3 antibody, Ubiquitin-activating enzyme E1C antibody, Ubiquitin-like modifier-activating enzyme 3 antibody

UniProt: Q8TBC4