Der Kaninchen Monoklonal anti-VLDLR Antikörper (Klon VLDLR-2896R) (ABIN7877497) detektiert spezifisch VLDLR in ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal dilution of the recombinant VLDL Receptor antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the recombinant VLDL Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
VLDLR
(Very Low Density Lipoprotein Receptor (VLDLR))
Andere Bezeichnung
VLDL Receptor
Hintergrund
VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.