Rekombinanter VLDLR Antikörper (C-Term)

Produktnummer ABIN7877494

Der Maus Monoklonal anti-VLDLR Antikörper (Klon rVLDLR-1337) (ABIN7877494) detektiert spezifisch VLDLR in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter VLDLR Antikörper (C-Term) (ABIN7877494)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VLDLR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: RVLDLR-1337

Produktdetails anti-VLDLR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: VLDLR Antibody / VLDL Receptor (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human protein fragment from the C-terminal region was used as the immunogen for the VLDLR antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the VLDLR antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the VLDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: VLDLR

Hintergrund: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin