PSPC1 Antikörper (AA 96-489)

Produktnummer ABIN7877253

Der Kaninchen Polyklonal anti-PSPC1 Antikörper wird verwendet zum Nachweis von PSPC1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für PSPC1 Antikörper (AA 96-489) (ABIN7877253)

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-PSPC1 Antikörper

Bindungsspezifität: AA 96-489

Verwendungszweck: Paraspeckle component 1 Antibody / PSPC1

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (E96-Q489) was used as the immunogen for the Paraspeckle component 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Paraspeckle component 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Paraspeckle component 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Andere Bezeichnung: Paraspeckle component 1

Hintergrund: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

UniProt: Q8WXF1