PSPC1 Antikörper (AA 10-90)

Produktnummer ABIN7230818

Der Kaninchen Polyklonal anti-PSPC1 Antikörper (ABIN7230818) detektiert spezifisch PSPC1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PSPC1 Antikörper (AA 10-90) (ABIN7230818)

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PSPC1 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Rabbit Anti-PSPC1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PSPC1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PSPC1 protein at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Andere Bezeichnung: PSPC1

Hintergrund: Paraspeckle component 1, Paraspeckle protein 1PSPC1 (Paraspeckle Component 1) is a Protein Coding gene. Diseases associated with PSPC1 include Eec Syndrome and Rapp-Hodgkin Syndrome. Among its related pathways are Circadian rythm related genes. PSPC1 encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by PSPC1 is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of PSPC1 results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

Molekulargewicht: 57kD

Gen-ID: 55269

UniProt: Q8WXF1