APOE Antikörper (AA 95-222)

Produktnummer ABIN7877220

Der Kaninchen Polyklonal anti-APOE Antikörper wird verwendet zum Nachweis von APOE in Proben von Human. Er wurde validiert für WB, ELISA, IF und FACS.

Kurzübersicht für APOE Antikörper (AA 95-222) (ABIN7877220)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-APOE Antikörper

Bindungsspezifität: AA 95-222

Verwendungszweck: Apolipoprotein E Antibody / APOE

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E95-Q222) was used as the immunogen for the Apolipoprotein E antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Apolipoprotein E antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Apolipoprotein E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: Apolipoprotein E

Hintergrund: Apolipoprotein E is also known as APOE, AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism