Rekombinanter Transferrin Receptor Antikörper (Extracellular)

Produktnummer ABIN7877191

Der Kaninchen Monoklonal anti-Transferrin Receptor Antikörper (Klon TFRC-2898R) (ABIN7877191) detektiert spezifisch Transferrin Receptor in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Transferrin Receptor Antikörper (Extracellular) (ABIN7877191)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TFRC-2898R

Produktdetails anti-Transferrin Receptor Antikörper

Bindungsspezifität: AA 94-212, Extracellular

Verwendungszweck: Recombinant CD71 Antibody / Transferrin Receptor / TFRC (Extracellular domain) (azide and preservative free)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant human partial protein (extracellular region, amino acids 94-212) was used as the immunogen for this recombinant CD71 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CD71 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis