PPP1R13B Antikörper (AA 901-1090)
Kurzübersicht für PPP1R13B Antikörper (AA 901-1090) (ABIN7877127)
Target
Alle PPP1R13B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 901-1090
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Verwendungszweck
- ASPP1 Antibody / PPP1R13B
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Aufreinigung
- Antigen affinity purified
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Immunogen
- An E.coli-derived human recombinant protein (F901-A1090) was used as the immunogen for the ASPP1 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the ASPP1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the ASPP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
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Andere Bezeichnung
- ASPP1
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Hintergrund
- Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
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UniProt
- Q96KQ4
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Pathways
- p53 Signalweg
Target
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