Aurora Kinase B Antikörper (AA 89-251)

Produktnummer ABIN7877054

Dieser Maus Monoklonal Antikörper detektiert spezifisch Aurora Kinase B in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Aurora Kinase B Antikörper (AA 89-251) (ABIN7877054)

Target: Aurora Kinase B (AURKB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aurora Kinase B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ARRK2-1

Produktdetails anti-Aurora Kinase B Antikörper

Bindungsspezifität: AA 89-251

Verwendungszweck: AURKB Antibody / Aurora B

Aufreinigung: Protein G affinity

Immunogen: Amino acids 89-251 were used as the immunogen for this AURKB antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the AURKB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Andere Bezeichnung: AURKB

Hintergrund: Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]

UniProt: Q96GD4

Pathways: T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades