WISP2 Antikörper (AA 87-116)

Produktnummer ABIN7877011

Der Kaninchen Polyklonal anti-WISP2 Antikörper (ABIN7877011) detektiert spezifisch WISP2 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für WISP2 Antikörper (AA 87-116) (ABIN7877011)

Target: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-WISP2 Antikörper

Bindungsspezifität: AA 87-116

Verwendungszweck: WISP-2 Antibody / WNT1-inducible-signaling pathway protein 2 / CCN5

Immunogen: A portion of amino acids 87-116 from the human protein was used as the immunogen for this WISP-2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the WISP-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the WISP-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu WISP2

Target: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Andere Bezeichnung: WISP-2

Hintergrund: CCN5, also known as WISP-2 (Wnt-1-induced secreted protein 2), is a member of the CCN family of proteins that are involved in cell growth, differentiation, and migration. It is known for its ability to modulate signaling pathways that regulate various cellular activities, making it a key player in maintaining homeostasis in tissues. One of the primary functions of CCN5 is its role in regulating the growth and development of tissues, particularly in the cardiovascular system. Studies have shown that CCN5 can protect against cardiac fibrosis and hypertrophy, making it a potential therapeutic target for heart-related diseases. Furthermore, CCN5 has been found to have anti-inflammatory properties, making it a promising candidate for the treatment of inflammatory conditions. Its ability to regulate immune responses and modulate cytokine production highlights its potential as a target for managing inflammatory disorders. CCN5 has also been implicated in the regulation of metabolic processes and energy homeostasis. Research has shown that CCN5 can influence lipid metabolism and insulin sensitivity, suggesting its potential use in combating metabolic disorders such as obesity and diabetes.

UniProt: O76076

Pathways: WNT Signalweg, Growth Factor Binding