SIGLEC5 Antikörper (AA 8-39)
Kurzübersicht für SIGLEC5 Antikörper (AA 8-39) (ABIN7876834)
Target
Alle SIGLEC5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 8-39
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Verwendungszweck
- SIGLEC5 Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 8-39 from the human protein was used as the immunogen for the SIGLEC5 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the SIGLEC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the SIGLEC5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
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Andere Bezeichnung
- SIGLEC5
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Hintergrund
- SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differenciation.
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UniProt
- O15389
Target
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