SIGLEC5 Antikörper (AA 17-230)
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- Target Alle SIGLEC5 Antikörper anzeigen
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
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Bindungsspezifität
- AA 17-230
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SIGLEC5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. coli.
- Klon
- 3F5A3
- Isotyp
- IgG2a
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- Andere Bezeichnung
- CD170 (SIGLEC5 Produkte)
- Synonyme
- CD170 antikoerper, CD33L2 antikoerper, OB-BP2 antikoerper, OBBP2 antikoerper, SIGLEC-5 antikoerper, sialic acid binding Ig like lectin 5 antikoerper, sialic acid-binding Ig-like lectin 5 antikoerper, sialic acid binding Ig-like lectin 5 antikoerper, SIGLEC5 antikoerper, LOC100597560 antikoerper, Siglec5 antikoerper
- Hintergrund
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Description: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Aliases: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5
- Molekulargewicht
- 60.7 kDa
- Gen-ID
- 8778
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