SAV1 Antikörper (AA 8-320)

Produktnummer ABIN7876818

Der Kaninchen Polyklonal anti-SAV1 Antikörper wird verwendet zum Nachweis von SAV1 in Proben von Human. Er wurde validiert für WB, ELISA, IHC (p) und FACS.

Kurzübersicht für SAV1 Antikörper (AA 8-320) (ABIN7876818)

Target: SAV1 (Salvador Homolog 1 (SAV1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-SAV1 Antikörper

Bindungsspezifität: AA 8-320

Verwendungszweck: SAV1 Antibody / Protein salvador homolog 1 / WW45

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K8-H320) was used as the immunogen for the SAV1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SAV1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SAV1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SAV1

Target: SAV1 (Salvador Homolog 1 (SAV1))

Andere Bezeichnung: SAV1

Hintergrund: Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

UniProt: Q9H4B6

Pathways: Stem Cell Maintenance