OTC Antikörper (AA 71-98)

Produktnummer ABIN7876612

Der Kaninchen Polyklonal anti-OTC Antikörper (ABIN7876612) detektiert spezifisch OTC in WB, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für OTC Antikörper (AA 71-98) (ABIN7876612)

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OTC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-OTC Antikörper

Bindungsspezifität: AA 71-98

Verwendungszweck: Ornithine transcarbamylase Antibody / OTCase / OTC

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 71-98 from the human protein was used as the immunogen for the Ornithine transcarbamylase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Ornithine transcarbamylase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Ornithine transcarbamylase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu OTC

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Andere Bezeichnung: Ornithine transcarbamylase

Hintergrund: Ornithine transcarbamylase is an enzyme that is responsible for catalyzing the reaction between ornithine and carbamoyl phosphate, ultimately forming citrulline. Citrulline then goes on to participate in the urea cycle, where it helps convert toxic ammonia into urea, which can be safely excreted by the body. A deficiency in this enzyme can lead to a rare genetic disorder known as ornithine transcarbamylase deficiency. Individuals with this condition are unable to properly metabolize ammonia, leading to a buildup of toxic levels in the blood. This can result in a range of symptoms, from mild to severe, including fatigue, seizures, and even coma if left untreated.

UniProt: P00480