Rekombinanter ACE2 Antikörper (AA 705-805)

Produktnummer ABIN7876592

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch ACE2 in ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter ACE2 Antikörper (AA 705-805) (ABIN7876592)

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ACE2-8748R

Produktdetails anti-ACE2 Antikörper

Bindungsspezifität: AA 705-805

Verwendungszweck: Angiotensin Converting Enzyme 2 Antibody / ACE2

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 705-805) from the human protein was used as the immunogen for the Angiotensin Converting Enzyme 2 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Angiotensin Converting Enzyme 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Angiotensin Converting Enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: Angiotensin Converting Enzyme 2

Hintergrund: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour