Der Kaninchen Monoklonal anti-RRM1 Antikörper (Klon RRM1-4372R) (ABIN7876549) detektiert spezifisch RRM1 in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal dilution of the RRM1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the RRM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
RRM1
(Ribonucleotide Reductase M1 (RRM1))
Andere Bezeichnung
RRM1
Hintergrund
Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.