RRM1 Antikörper (Center)

Produktnummer ABIN2854856

Produktdetails anti-RRM1 Antikörper

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to RRM1 (ribonucleotide reductase M1)
RRM1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NIH-3T3 , Raw264.7 , C2C12

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.49 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Andere Bezeichnung: ribonucleotide reductase M1 (RRM1 Produkte)

Synonyme: CG5371 antikoerper, DmRNR1 antikoerper, Dmel\\CG5371 antikoerper, RNR1 antikoerper, RnrM1 antikoerper, RntL antikoerper, l(2)k06709 antikoerper, XRRM1 antikoerper, R1 antikoerper, RIR1 antikoerper, RR1 antikoerper, CHUNP6866 antikoerper, cb396 antikoerper, cb838 antikoerper, r1 antikoerper, sb:cb548 antikoerper, wu:fb39b07 antikoerper, wu:fi14b02 antikoerper, wu:fk95f07 antikoerper, ribonucleotide reductase catalytic subunit M1 antikoerper, Ribonucleoside diphosphate reductase large subunit antikoerper, ribonucleoside-diphosphate reductase large subunit antikoerper, ribonucleotide reductase M1 L homeolog antikoerper, ribonucleotide reductase M1 antikoerper, ribonucleotide reductase M1 polypeptide antikoerper, RRM1 antikoerper, RnrL antikoerper, LOC100472317 antikoerper, rrm1 antikoerper, rrm1.L antikoerper, Rrm1 antikoerper

Hintergrund: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Cellular Localization: Cytoplasm

Molekulargewicht: 90 kDa

Gen-ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity